Sayadaw U Osadha was born on November 19, 1961 in Tha Zi village, Myanmar. He became a novice in 1974 and was ordained in 1981. He has been a Dhamma Teacher since 1986. He was a resident monk from 1995 to July 1997 at Sasana Yeiktha (main Mahasi Meditation Center in Yangon), giving Dhamma Talks and conducting meditation sessions.

He has been a Resident monk at Dhammananda Vihara Monastery in Half Moon Bay, California, since July 1997, giving Dhamma talks and teaching Vipassana meditaion in Burmese and English.